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CD39-adenosinergic axis in renal pathophysiology and therapeutics

Extracellular ATP interacts with purinergic type 2 (P2) receptors and elicits many crucial biological functions. Extracellular ATP is sequentially hydrolyzed to ADP and AMP by the actions of defined nucleotidases, such as CD39, and AMP is converted to adenosine, largely by CD73, an ecto-5′-nucleotid...

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Bibliografiske detaljer
Udgivet i:Purinergic Signal
Main Authors: Kishore, Bellamkonda K., Robson, Simon C., Dwyer, Karen M.
Format: Artigo
Sprog:Inglês
Udgivet: Springer Netherlands 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940625/
https://ncbi.nlm.nih.gov/pubmed/29332180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-017-9596-x
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