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CD39-adenosinergic axis in renal pathophysiology and therapeutics

Extracellular ATP interacts with purinergic type 2 (P2) receptors and elicits many crucial biological functions. Extracellular ATP is sequentially hydrolyzed to ADP and AMP by the actions of defined nucleotidases, such as CD39, and AMP is converted to adenosine, largely by CD73, an ecto-5′-nucleotid...

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Detalhes bibliográficos
Publicado no:Purinergic Signal
Main Authors: Kishore, Bellamkonda K., Robson, Simon C., Dwyer, Karen M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940625/
https://ncbi.nlm.nih.gov/pubmed/29332180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-017-9596-x
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