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T –cell specific defect in expression of the NTPDase CD39 as a biomarker for lupus

Regulatory T cells (T(regs)) are critical for maintenance of peripheral tolerance via suppression of T-cell responses, and absence of T(regs) results in autoimmunity. The role of aberrations in the T(reg) pool for the development of systemic lupus erythamatosus (SLE, lupus) remains uncertain. T(reg)...

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Detalhes bibliográficos
Main Authors: Loza, Matthew J., Anderson, A. Shane, O’Rourke, Kenneth S., Wood, James, Khan, Islam U.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3168146/
https://ncbi.nlm.nih.gov/pubmed/21763644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2011.06.010
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