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Cystic fibrosis remodels the regulation of purinergic signaling by NTPDase1 (CD39) and NTPDase3

Airway defenses are regulated by a complex purinergic signaling network located on the epithelial surfaces, where ATP stimulates the clearance of mucin and pathogens. The present study shows that the obstructive disease cystic fibrosis (CF) affects the activity, expression, and tissue distribution o...

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Detalhes bibliográficos
Main Authors: Fausther, Michel, Pelletier, Julie, Ribeiro, Carla M., Sévigny, Jean, Picher, Maryse
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886614/
https://ncbi.nlm.nih.gov/pubmed/20190036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00019.2010
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