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Role of the ectonucleotidase NTPDase2 in taste bud function

Taste buds are unusual in requiring ATP as a transmitter to activate sensory nerve fibers. In response to taste stimuli, taste cells release ATP, activating purinergic receptors containing the P2X2 and P2X3 subunits on taste nerves. In turn, the released ATP is hydrolyzed to ADP by a plasma membrane...

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Detalhes bibliográficos
Main Authors: Vandenbeuch, Aurelie, Anderson, Catherine B., Parnes, Jason, Enjyoji, Keiichi, Robson, Simon C., Finger, Thomas E., Kinnamon, Sue C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767538/
https://ncbi.nlm.nih.gov/pubmed/23959882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1309468110
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