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The small molecule ferristatin II induces hepatic hepcidin expression in vivo and in vitro
Previous studies have shown that administration of ferristatin II to rats is associated with decreased serum iron, reduced transferrin saturation, and increased hepatic hepcidin expression. BMP and IL-6 signaling act via Smad and Stat3 transcription factors, respectively, to increase expression of h...
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| Pubblicato in: | Am J Physiol Gastrointest Liver Physiol |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Physiological Society
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4469869/ https://ncbi.nlm.nih.gov/pubmed/25907691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00324.2014 |
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