The small molecule ferristatin II induces hepatic hepcidin expression in vivo and in vitro

Previous studies have shown that administration of ferristatin II to rats is associated with decreased serum iron, reduced transferrin saturation, and increased hepatic hepcidin expression. BMP and IL-6 signaling act via Smad and Stat3 transcription factors, respectively, to increase expression of h...

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Detalhes bibliográficos
Publicado no:Am J Physiol Gastrointest Liver Physiol
Main Authors: Alkhateeb, Ahmed A., Buckett, Peter D., Gardeck, Andrew M., Kim, Jonghan, Byrne, Shaina L., Fraenkel, Paula G., Wessling-Resnick, Marianne
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
Assuntos:
Hormones and Signaling
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469869/
https://ncbi.nlm.nih.gov/pubmed/25907691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00324.2014
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