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Ferristatin II Promotes Degradation of Transferrin Receptor-1 In Vitro and In Vivo
Previous studies have shown that the small molecule iron transport inhibitor ferristatin (NSC30611) acts by down-regulating transferrin receptor-1 (TfR1) via receptor degradation. In this investigation, we show that another small molecule, ferristatin II (NSC8679), acts in a similar manner to degrad...
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| Asıl Yazarlar: | , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Public Library of Science
2013
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3720890/ https://ncbi.nlm.nih.gov/pubmed/23894616 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070199 |
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