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Ferristatin II Promotes Degradation of Transferrin Receptor-1 In Vitro and In Vivo
Previous studies have shown that the small molecule iron transport inhibitor ferristatin (NSC30611) acts by down-regulating transferrin receptor-1 (TfR1) via receptor degradation. In this investigation, we show that another small molecule, ferristatin II (NSC8679), acts in a similar manner to degrad...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3720890/ https://ncbi.nlm.nih.gov/pubmed/23894616 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070199 |
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