Ferristatin II Promotes Degradation of Transferrin Receptor-1 In Vitro and In Vivo

Previous studies have shown that the small molecule iron transport inhibitor ferristatin (NSC30611) acts by down-regulating transferrin receptor-1 (TfR1) via receptor degradation. In this investigation, we show that another small molecule, ferristatin II (NSC8679), acts in a similar manner to degrad...

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Bibliografiska uppgifter
Huvudupphovsmän: Byrne, Shaina L., Buckett, Peter D., Kim, Jonghan, Luo, Flora, Sanford, Jack, Chen, Juxing, Enns, Caroline, Wessling-Resnick, Marianne
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2013
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3720890/
https://ncbi.nlm.nih.gov/pubmed/23894616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070199
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