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Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression
Background: The number of Mendelian randomization analyses including large numbers of genetic variants is rapidly increasing. This is due to the proliferation of genome-wide association studies, and the desire to obtain more precise estimates of causal effects. However, some genetic variants may not...
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| Publicado en: | Int J Epidemiol |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4469799/ https://ncbi.nlm.nih.gov/pubmed/26050253 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ije/dyv080 |
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