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Detecting and correcting for bias in Mendelian randomization analyses using Gene-by-Environment interactions
BACKGROUND: Mendelian randomization (MR) has developed into an established method for strengthening causal inference and estimating causal effects, largely due to the proliferation of genome-wide association studies. However, genetic instruments remain controversial, as horizontal pleiotropic effect...
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| Pubblicato in: | Int J Epidemiol |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6659360/ https://ncbi.nlm.nih.gov/pubmed/30462199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ije/dyy204 |
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