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Discovery of allostery in PKA signaling

Cyclic AMP (cAMP)-dependent protein kinase (PKA) was the second protein kinase to be identified, and the PKA catalytic (C)-subunit serves as a prototype for the large protein kinase superfamily that contains over 500 gene products. The protein kinases regulate many biological functions in eukaryotic...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biophys Rev
Hauptverfasser: Zhang, Ping, Kornev, Alexandr P., Wu, Jian, Taylor, Susan S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Berlin Heidelberg 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469037/
https://ncbi.nlm.nih.gov/pubmed/26097522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12551-015-0170-x
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