טוען...

Expression of UDP-Glucuronosyltransferase 1 (UGT1) and Glucuronidation Activity toward Endogenous Substances in Humanized UGT1 Mouse Brain

Although UDP-glucuronosyltransferases (UGTs) are important phase II drug-metabolizing enzymes, they are also involved in the metabolism of endogenous compounds. Certain substrates of UGTs, such as serotonin and estradiol, play important roles in the brain. However, the expression of UGTs in the huma...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Drug Metab Dispos
Main Authors: Kutsuno, Yuki, Hirashima, Rika, Sakamoto, Masaya, Ushikubo, Hiroko, Michimae, Hirofumi, Itoh, Tomoo, Tukey, Robert H., Fujiwara, Ryoichi
פורמט: Artigo
שפה:Inglês
יצא לאור: The American Society for Pharmacology and Experimental Therapeutics 2015
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468441/
https://ncbi.nlm.nih.gov/pubmed/25953521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.115.063719
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