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Molecular modeling of the human P2Y(14) receptor: A template for structure-based design of selective agonist ligands
The P2Y(14) receptor (P2Y(14)R) is a G(i) protein-coupled receptor that is activated by uracil nucleotides UDP and UDP-glucose. The P2Y(14)R structure has yet to be solved through X-ray crystallography, but the recent agonist-bound crystal structure of the P2Y(12)R provides a potentially suitable te...
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| Udgivet i: | Bioorg Med Chem |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4468048/ https://ncbi.nlm.nih.gov/pubmed/25868749 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2015.03.042 |
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