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Identification of potent and compartment-selective small molecule furin inhibitors using cell-based assays
The proprotein convertase furin is implicated in a variety of pathogenic processes such as bacterial toxin activation, viral propagation, and cancer. Several groups have identified non-peptide compounds with high inhibitory potency against furin in vitro, although their efficacy in various cellbased...
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| Publicat a: | Biochem Pharmacol |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4468025/ https://ncbi.nlm.nih.gov/pubmed/26003844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2015.05.008 |
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