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Identification of potent and compartment-selective small molecule furin inhibitors using cell-based assays
The proprotein convertase furin is implicated in a variety of pathogenic processes such as bacterial toxin activation, viral propagation, and cancer. Several groups have identified non-peptide compounds with high inhibitory potency against furin in vitro, although their efficacy in various cellbased...
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| Pubblicato in: | Biochem Pharmacol |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4468025/ https://ncbi.nlm.nih.gov/pubmed/26003844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2015.05.008 |
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