Piperlongumine selectively kills hepatocellular carcinoma cells and preferentially inhibits their invasion via ROS-ER-MAPKs-CHOP

Hepatocellular carcinomas (HCC) are highly malignant and aggressive tumors lack of effective therapeutic drugs. Piperlongumine (PL), a natural product isolated from longer pepper plants, is recently identified as a potent cytotoxic compound highly selective to cancer cells. Here, we reported that PL...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Chen, Yong, Liu, Ju Mei, Xiong, Xin Xin, Qiu, Xin Yao, Pan, Feng, Liu, Di, Lan, Shu Jue, Jin, Si, Yu, Shang Bin, Chen, Xiao Qian
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467445/
https://ncbi.nlm.nih.gov/pubmed/25788268
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