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Piperlongumine induces apoptotic and autophagic death of the primary myeloid leukemia cells from patients via activation of ROS-p38/JNK pathways
AIM: To investigate the effects of piperlongumine (PL), an anticancer alkaloid from long pepper plants, on the primary myeloid leukemia cells from patients and the mechanisms of action. METHODS: Human BM samples were obtained from 9 patients with acute or chronic myeloid leukemias and 2 patients wit...
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| Publicado no: | Acta Pharmacol Sin |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4349924/ https://ncbi.nlm.nih.gov/pubmed/25619389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2014.141 |
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