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Molecular Characterization of Inflammatory Myofibroblastic Tumors with Frequent ALK and ROS1 Fusions and Rare Novel RET Gene Rearrangement

Approximately 50% of conventional IMTs harbor ALK gene rearrangement and overexpress ALK. Recently gene fusions involving other kinases have been implicated in the pathogenesis of IMT, including ROS1 and in one patient PDGFRB. However, it remains uncertain if the emerging genotypes correlate with cl...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Am J Surg Pathol
Egile Nagusiak: Antonescu, Cristina R, Suurmeijer, Albert JH, Zhang, Lei, Sung, Yun-Shao, Jungbluth, Achim A, Travis, William D, Al-Ahmadie, Hikmat, Fletcher, Christopher DM, Alaggio, Rita
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4465992/
https://ncbi.nlm.nih.gov/pubmed/25723109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PAS.0000000000000404
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