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Expanding the Molecular Characterization of Thoracic Inflammatory Myofibroblastic Tumors beyond ALK gene rearrangements

BACKGROUND: Half of inflammatory myofibroblastic tumors (IMTs) regardless of anatomic location harbor ALK gene rearrangements and overexpress ALK protein. The wide application of next generation sequencing (NGS) and the clinical benefit to tyrosine kinase inhibitors have opened new opportunities for...

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Bibliografske podrobnosti
izdano v:J Thorac Oncol
Main Authors: Chang, Jason C, Zhang, Lei, Drilon, Alexander E, Chi, Ping, Alaggio, Rita, Borsu, Laetitia, Benayed, Ryma, Travis, William D, Ladanyi, Marc, Antonescu, Cristina R
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6486847/
https://ncbi.nlm.nih.gov/pubmed/30550870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtho.2018.12.003
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