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Expanding the Molecular Characterization of Thoracic Inflammatory Myofibroblastic Tumors beyond ALK gene rearrangements

BACKGROUND: Half of inflammatory myofibroblastic tumors (IMTs) regardless of anatomic location harbor ALK gene rearrangements and overexpress ALK protein. The wide application of next generation sequencing (NGS) and the clinical benefit to tyrosine kinase inhibitors have opened new opportunities for...

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Detalhes bibliográficos
Publicado no:J Thorac Oncol
Main Authors: Chang, Jason C, Zhang, Lei, Drilon, Alexander E, Chi, Ping, Alaggio, Rita, Borsu, Laetitia, Benayed, Ryma, Travis, William D, Ladanyi, Marc, Antonescu, Cristina R
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6486847/
https://ncbi.nlm.nih.gov/pubmed/30550870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtho.2018.12.003
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