Crizotinib in ALK-Rearranged Inflammatory Myofibroblastic Tumor

Inflammatory myofibroblastic tumor (IMT) is a distinctive mesenchymal neoplasm characterized by a spindle-cell proliferation with an inflammatory infiltrate. Approximately half of IMTs carry rearrangements of the anaplastic lymphoma kinase (ALK) locus on chromosome 2p23, causing aberrant ALK express...

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Main Authors: Butrynski, James E., D’Adamo, David R., Hornick, Jason L., Cin, Paola Dal, Antonescu, Cristina R., Jhanwar, Suresh C., Ladanyi, Marc, Capelletti, Marzia, Rodig, Scott J., Ramaiya, Nikhil, Kwak, Eunice L., Clark, Jeffrey W., Wilner, Keith D., Christensen, James G., Jänne, Pasi A., Maki, Robert G., Demetri, George D., Shapiro, Geoffrey I.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014292/
https://ncbi.nlm.nih.gov/pubmed/20979472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1007056
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