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Crizotinib in ALK-Rearranged Inflammatory Myofibroblastic Tumor

Inflammatory myofibroblastic tumor (IMT) is a distinctive mesenchymal neoplasm characterized by a spindle-cell proliferation with an inflammatory infiltrate. Approximately half of IMTs carry rearrangements of the anaplastic lymphoma kinase (ALK) locus on chromosome 2p23, causing aberrant ALK express...

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Auteurs principaux: Butrynski, James E., D’Adamo, David R., Hornick, Jason L., Cin, Paola Dal, Antonescu, Cristina R., Jhanwar, Suresh C., Ladanyi, Marc, Capelletti, Marzia, Rodig, Scott J., Ramaiya, Nikhil, Kwak, Eunice L., Clark, Jeffrey W., Wilner, Keith D., Christensen, James G., Jänne, Pasi A., Maki, Robert G., Demetri, George D., Shapiro, Geoffrey I.
Format: Artigo
Langue:Inglês
Publié: 2010
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014292/
https://ncbi.nlm.nih.gov/pubmed/20979472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1007056
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