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Crizotinib in ALK-Rearranged Inflammatory Myofibroblastic Tumor

Inflammatory myofibroblastic tumor (IMT) is a distinctive mesenchymal neoplasm characterized by a spindle-cell proliferation with an inflammatory infiltrate. Approximately half of IMTs carry rearrangements of the anaplastic lymphoma kinase (ALK) locus on chromosome 2p23, causing aberrant ALK express...

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Hlavní autoři: Butrynski, James E., D’Adamo, David R., Hornick, Jason L., Cin, Paola Dal, Antonescu, Cristina R., Jhanwar, Suresh C., Ladanyi, Marc, Capelletti, Marzia, Rodig, Scott J., Ramaiya, Nikhil, Kwak, Eunice L., Clark, Jeffrey W., Wilner, Keith D., Christensen, James G., Jänne, Pasi A., Maki, Robert G., Demetri, George D., Shapiro, Geoffrey I.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014292/
https://ncbi.nlm.nih.gov/pubmed/20979472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1007056
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