Molecular Characterization of Inflammatory Myofibroblastic Tumors with Frequent ALK and ROS1 Fusions and Rare Novel RET Gene Rearrangement

Approximately 50% of conventional IMTs harbor ALK gene rearrangement and overexpress ALK. Recently gene fusions involving other kinases have been implicated in the pathogenesis of IMT, including ROS1 and in one patient PDGFRB. However, it remains uncertain if the emerging genotypes correlate with cl...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Am J Surg Pathol
Hoofdauteurs: Antonescu, Cristina R, Suurmeijer, Albert JH, Zhang, Lei, Sung, Yun-Shao, Jungbluth, Achim A, Travis, William D, Al-Ahmadie, Hikmat, Fletcher, Christopher DM, Alaggio, Rita
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4465992/
https://ncbi.nlm.nih.gov/pubmed/25723109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PAS.0000000000000404
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items