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Development and optimization of a self-microemulsifying drug delivery system for ator vastatin calcium by using d-optimal mixture design
In this study, we developed and optimized a self-microemulsifying drug delivery system (SMEDDS) formulation for improving the dissolution and oral absorption of atorvastatin calcium (ATV), a poorly water-soluble drug. Solubility and emulsification tests were performed to select a suitable combinatio...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Int J Nanomedicine |
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| Κύριοι συγγραφείς: | , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Dove Medical Press
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4462857/ https://ncbi.nlm.nih.gov/pubmed/26089663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S83520 |
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