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Self-microemulsifying drug delivery system (SMEDDS) for improved oral delivery and photostability of methotrexate
Purpose: The objective of this study was to exploit a novel methotrexate (MTX)-loaded solid self-microemulsifying drug delivery system (SMEDDS) with enhanced bioavailability and photostability. Materials and methods: The optimized liquid SMEDDS was composed of castor oil, Tween(®) 80, and Plurol(®)...
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| Publicado no: | Int J Nanomedicine |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6617838/ https://ncbi.nlm.nih.gov/pubmed/31308665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S211014 |
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