Development and optimization of a self-microemulsifying drug delivery system for ator vastatin calcium by using d-optimal mixture design

In this study, we developed and optimized a self-microemulsifying drug delivery system (SMEDDS) formulation for improving the dissolution and oral absorption of atorvastatin calcium (ATV), a poorly water-soluble drug. Solubility and emulsification tests were performed to select a suitable combinatio...

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Bibliografiske detaljer
Udgivet i:Int J Nanomedicine
Main Authors: Yeom, Dong Woo, Song, Ye Seul, Kim, Sung Rae, Lee, Sang Gon, Kang, Min Hyung, Lee, Sangkil, Choi, Young Wook
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2015
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4462857/
https://ncbi.nlm.nih.gov/pubmed/26089663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S83520
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