Optimized formulation of solid self-microemulsifying sirolimus delivery systems

BACKGROUND: The aim of this study was to develop an optimized solid self-microemulsifying drug delivery system (SMEDDS) formulation for sirolimus to enhance its solubility, stability, and bioavailability. METHODS: Excipients used for enhancing the solubility and stability of sirolimus were screened....

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Autors principals: Cho, Wonkyung, Kim, Min-Soo, Kim, Jeong-Soo, Park, Junsung, Park, Hee Jun, Cha, Kwang-Ho, Park, Jeong-Sook, Hwang, Sung-Joo
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2013
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3639716/
https://ncbi.nlm.nih.gov/pubmed/23641156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S43299
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