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Optimized formulation of solid self-microemulsifying sirolimus delivery systems
BACKGROUND: The aim of this study was to develop an optimized solid self-microemulsifying drug delivery system (SMEDDS) formulation for sirolimus to enhance its solubility, stability, and bioavailability. METHODS: Excipients used for enhancing the solubility and stability of sirolimus were screened....
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3639716/ https://ncbi.nlm.nih.gov/pubmed/23641156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S43299 |
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