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Solid Sirolimus Self-microemulsifying Drug Delivery System: Development and Evaluation of Tablets with Sustained Release Property

The clinical application of sirolimus (SRL) as an immunosuppressive agent is largely hampered by its narrow therapeutic range. This study focused on developing SRL tablets with a sustained release profile for better safety. SRL was highly water insoluble and its solubility has been efficiently enhan...

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Detalhes bibliográficos
Publicado no:Iran J Pharm Res
Main Authors: Tao, Chun, Wen, Xu, Zhang, Qian, Song, Hongtao
Formato: Artigo
Idioma:Inglês
Publicado em: Shaheed Beheshti University of Medical Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059041/
https://ncbi.nlm.nih.gov/pubmed/32184836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22037/ijpr.2019.1100847
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