Solid formulation of a supersaturable self-microemulsifying drug delivery system for valsartan with improved dissolution and bioavailability

In order to improve the dissolution and oral bioavailability of valsartan (VST), and reduce the required volume for treatment, we previously formulated a supersaturable self-microemulsifying drug delivery system (SuSMEDDS) composed of VST (80 mg), Capmul(®) MCM (13.2 mg), Tween(®) 80 (59.2 mg), Tran...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Yeom, Dong Woo, Chae, Bo Ram, Kim, Jin Han, Chae, Jun Soo, Shin, Dong Jun, Kim, Chang Hyun, Kim, Sung Rae, Choi, Ji Ho, Song, Seh Hyon, Oh, Dongho, Sohn, Se Il, Choi, Young Wook
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706875/
https://ncbi.nlm.nih.gov/pubmed/29212229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21691
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