Solid formulation of a supersaturable self-microemulsifying drug delivery system for valsartan with improved dissolution and bioavailability

In order to improve the dissolution and oral bioavailability of valsartan (VST), and reduce the required volume for treatment, we previously formulated a supersaturable self-microemulsifying drug delivery system (SuSMEDDS) composed of VST (80 mg), Capmul(®) MCM (13.2 mg), Tween(®) 80 (59.2 mg), Tran...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Yeom, Dong Woo, Chae, Bo Ram, Kim, Jin Han, Chae, Jun Soo, Shin, Dong Jun, Kim, Chang Hyun, Kim, Sung Rae, Choi, Ji Ho, Song, Seh Hyon, Oh, Dongho, Sohn, Se Il, Choi, Young Wook
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706875/
https://ncbi.nlm.nih.gov/pubmed/29212229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21691
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