Solid formulation of a supersaturable self-microemulsifying drug delivery system for valsartan with improved dissolution and bioavailability

In order to improve the dissolution and oral bioavailability of valsartan (VST), and reduce the required volume for treatment, we previously formulated a supersaturable self-microemulsifying drug delivery system (SuSMEDDS) composed of VST (80 mg), Capmul(®) MCM (13.2 mg), Tween(®) 80 (59.2 mg), Tran...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncotarget
Prif Awduron: Yeom, Dong Woo, Chae, Bo Ram, Kim, Jin Han, Chae, Jun Soo, Shin, Dong Jun, Kim, Chang Hyun, Kim, Sung Rae, Choi, Ji Ho, Song, Seh Hyon, Oh, Dongho, Sohn, Se Il, Choi, Young Wook
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2017
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706875/
https://ncbi.nlm.nih.gov/pubmed/29212229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21691
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