Supersaturable solid self-microemulsifying drug delivery system: precipitation inhibition and bioavailability enhancement

Solid self-emulsifying drug delivery system (SSEDDS), which incorporates liquid SEDDS into a solid dosage form, has been recently introduced to improve the oral bioavail-ability of poorly water-soluble drugs. However, supersaturated drug generated by SSEDDS is thermodynamically unstable and tends to...

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Bibliographic Details
Published in:Int J Nanomedicine
Main Authors: Quan, Guilan, Niu, Boyi, Singh, Vikramjeet, Zhou, Yixian, Wu, Chuan-Yu, Pan, Xin, Wu, Chuanbin
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2017
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732552/
https://ncbi.nlm.nih.gov/pubmed/29263669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S149717
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