Solid formulation of a supersaturable self-microemulsifying drug delivery system for valsartan with improved dissolution and bioavailability

In order to improve the dissolution and oral bioavailability of valsartan (VST), and reduce the required volume for treatment, we previously formulated a supersaturable self-microemulsifying drug delivery system (SuSMEDDS) composed of VST (80 mg), Capmul(®) MCM (13.2 mg), Tween(®) 80 (59.2 mg), Tran...

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Detalles Bibliográficos
Publicado en:Oncotarget
Autores principales: Yeom, Dong Woo, Chae, Bo Ram, Kim, Jin Han, Chae, Jun Soo, Shin, Dong Jun, Kim, Chang Hyun, Kim, Sung Rae, Choi, Ji Ho, Song, Seh Hyon, Oh, Dongho, Sohn, Se Il, Choi, Young Wook
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706875/
https://ncbi.nlm.nih.gov/pubmed/29212229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21691
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