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Modulation of HIV Protease Flexibility by the T80N Mutation
The flexibility of HIV protease plays a critical role in enabling enzymatic activity and is required for substrate access to the active site. While the importance of flexibility in the flaps that cover the active site is well known, flexibility in other parts of the enzyme is also critical for funct...
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| Udgivet i: | Proteins |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4461556/ https://ncbi.nlm.nih.gov/pubmed/25488402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24737 |
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