Canine Distemper Virus and Measles Virus Fusion Glycoprotein Trimers: Partial Membrane-Proximal Ectodomain Cleavage Enhances Function

The trimeric fusion (F) glycoproteins of morbilliviruses are activated by furin cleavage of the precursor F(0) into the F(1) and F(2) subunits. Here we show that an additional membrane-proximal cleavage occurs and modulates F protein function. We initially observed that the ectodomain of approximate...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	von Messling, Veronika, Milosevic, Dragana, Devaux, Patricia, Cattaneo, Roberto
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2004
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC446110/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15254162/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.15.7894-7903.2004
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