Canine Distemper Virus and Measles Virus Fusion Glycoprotein Trimers: Partial Membrane-Proximal Ectodomain Cleavage Enhances Function

The trimeric fusion (F) glycoproteins of morbilliviruses are activated by furin cleavage of the precursor F(0) into the F(1) and F(2) subunits. Here we show that an additional membrane-proximal cleavage occurs and modulates F protein function. We initially observed that the ectodomain of approximate...

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-д хэвлэсэн:	J Virol
Үндсэн зохиолчид:	von Messling, Veronika, Milosevic, Dragana, Devaux, Patricia, Cattaneo, Roberto
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	American Society for Microbiology (ASM) 2004
Нөхцлүүд:	Virus-Cell Interactions
Онлайн хандалт:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC446110/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15254162/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.15.7894-7903.2004
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