Canine Distemper Virus and Measles Virus Fusion Glycoprotein Trimers: Partial Membrane-Proximal Ectodomain Cleavage Enhances Function

The trimeric fusion (F) glycoproteins of morbilliviruses are activated by furin cleavage of the precursor F(0) into the F(1) and F(2) subunits. Here we show that an additional membrane-proximal cleavage occurs and modulates F protein function. We initially observed that the ectodomain of approximate...

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Vydáno v:	J Virol
Hlavní autoři:	von Messling, Veronika, Milosevic, Dragana, Devaux, Patricia, Cattaneo, Roberto
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2004
Témata:	Virus-Cell Interactions
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC446110/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15254162/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.15.7894-7903.2004
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