Canine Distemper Virus and Measles Virus Fusion Glycoprotein Trimers: Partial Membrane-Proximal Ectodomain Cleavage Enhances Function

The trimeric fusion (F) glycoproteins of morbilliviruses are activated by furin cleavage of the precursor F(0) into the F(1) and F(2) subunits. Here we show that an additional membrane-proximal cleavage occurs and modulates F protein function. We initially observed that the ectodomain of approximate...

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Bibliografische Detailangaben

Veröffentlicht in:	J Virol
Hauptverfasser:	von Messling, Veronika, Milosevic, Dragana, Devaux, Patricia, Cattaneo, Roberto
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2004
Schlagworte:	Virus-Cell Interactions
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC446110/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15254162/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.15.7894-7903.2004
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