Canine Distemper Virus and Measles Virus Fusion Glycoprotein Trimers: Partial Membrane-Proximal Ectodomain Cleavage Enhances Function

The trimeric fusion (F) glycoproteins of morbilliviruses are activated by furin cleavage of the precursor F(0) into the F(1) and F(2) subunits. Here we show that an additional membrane-proximal cleavage occurs and modulates F protein function. We initially observed that the ectodomain of approximate...

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Detalles Bibliográficos

Publicado en:	J Virol
Autores principales:	von Messling, Veronika, Milosevic, Dragana, Devaux, Patricia, Cattaneo, Roberto
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 2004
Materias:	Virus-Cell Interactions
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC446110/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15254162/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.15.7894-7903.2004
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