A phase 2 consortium (P2C) trial of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP) for advanced adenocarcinoma of the pancreas

3-Aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP, Triapine(®)) is a novel small molecule inhibitor of ribonucleotide reductase (RR) with clinical signs of activity in pancreatic cancer. Therefore, the Phase 2 Consortium (P2C) initiated a trial (two single stage studies with planned interim a...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Invest New Drugs
Autores principales: Attia, Steven, Kolesar, Jill, Mahoney, Michelle R., Pitot, Henry C., Laheru, Daniel, Heun, James, Huang, Wei, Eickhoff, Jens, Erlichman, Charles, Holen, Kyle D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4461052/
https://ncbi.nlm.nih.gov/pubmed/18278438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-008-9123-6
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares