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Microglial internalization and degradation of pathological tau is enhanced by an anti-tau monoclonal antibody
Microglia have been shown to contribute to the clearance of brain amyloid β peptides (Aβ), the major component of amyloid plaques, in Alzheimer’s disease (AD). However, it is not known whether microglia play a similar role in the clearance of tau, the major component of neurofibrillary tangles (NFTs...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4460904/ https://ncbi.nlm.nih.gov/pubmed/26057852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11161 |
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