Vectored Intracerebral Immunization with the Anti-Tau Monoclonal Antibody PHF1 Markedly Reduces Tau Pathology in Mutant Tau Transgenic Mice

Passive immunization with anti-tau monoclonal antibodies has been shown by several laboratories to reduce age-dependent tau pathology and neurodegeneration in mutant tau transgenic mice. These studies have used repeated high weekly doses of various tau antibodies administered systemically for severa...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Liu, Wencheng, Zhao, Lingzhi, Blackman, Brittany, Parmar, Mayur, Wong, Man Ying, Woo, Thomas, Yu, Fangmin, Chiuchiolo, Maria J., Sondhi, Dolan, Kaminsky, Stephen M., Crystal, Ronald G., Paul, Steven M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601971/
https://ncbi.nlm.nih.gov/pubmed/27927959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2016-16.2016
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