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Membrane-mediated fibrillation and toxicity of the tau hexapeptide PHF6

The aggregation of the tau protein into neurofibrillary tangles is believed to correlate with cognitive decline in several neurodegenerative disorders, including Alzheimer's disease. Recent studies suggest that tau's interactions with the cell membrane could serve as a toxicity pathway and...

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Bibliografiska uppgifter
I publikationen:J Biol Chem
Huvudupphovsmän: Fanni, Adeline M., Vander Zanden, Crystal M., Majewska, Paulina V., Majewski, Jaroslaw, Chi, Eva Y.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6802503/
https://ncbi.nlm.nih.gov/pubmed/31439664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010003
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