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Passive immunotherapies targeting amyloid beta and tau oligomers in Alzheimer’s disease

Alzheimer’s disease (AD) is historically difficult to treat, in part due the inaccessible nature of brain pathology. Amyloid-β (Aβ) and tau proteins drive pathology by forming toxic oligomers that eventually deposit as insoluble amyloid plaques and neurofibrillary tangles. Recent clinical studies su...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Pharm Sci
Hauptverfasser: Vander Zanden, Crystal M., Chi, Eva Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6937375/
https://ncbi.nlm.nih.gov/pubmed/31647950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xphs.2019.10.024
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