Generation and characterization of new monoclonal antibodies targeting the PHF1 and AT8 epitopes on human tau

Tauopathies are a group of neurodegenerative disorders, including Alzheimer’s disease, defined by the presence of brain pathological inclusions comprised of abnormally aggregated and highly phosphorylated tau protein. The abundance of brain tau aggregates correlates with disease severity and select...

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Bibliografiske detaljer
Udgivet i:Acta Neuropathol Commun
Main Authors: Strang, Kevin H., Goodwin, Marshall S., Riffe, Cara, Moore, Brenda D., Chakrabarty, Paramita, Levites, Yona, Golde, Todd E., Giasson, Benoit I.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5537986/
https://ncbi.nlm.nih.gov/pubmed/28760159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-017-0458-0
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