Generation and characterization of new monoclonal antibodies targeting the PHF1 and AT8 epitopes on human tau

Tauopathies are a group of neurodegenerative disorders, including Alzheimer’s disease, defined by the presence of brain pathological inclusions comprised of abnormally aggregated and highly phosphorylated tau protein. The abundance of brain tau aggregates correlates with disease severity and select...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Strang, Kevin H., Goodwin, Marshall S., Riffe, Cara, Moore, Brenda D., Chakrabarty, Paramita, Levites, Yona, Golde, Todd E., Giasson, Benoit I.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5537986/
https://ncbi.nlm.nih.gov/pubmed/28760159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-017-0458-0
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