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Novel monoclonal antibodies targeting the microtubule-binding domain of human tau

Tauopathies including Alzheimer’s disease and Progressive Supranuclear Palsy are a diverse group of progressive neurodegenerative disorders pathologically defined by inclusions containing aberrantly aggregated, post-translationally modified tau. The tau pathology burden correlates with neurodegenera...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Croft, Cara L., Moore, Brenda D., Ran, Yong, Chakrabarty, Paramita, Levites, Yona, Golde, Todd E., Giasson, Benoit I.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880389/
https://ncbi.nlm.nih.gov/pubmed/29608591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0195211
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