Novel monoclonal antibodies targeting the microtubule-binding domain of human tau

Tauopathies including Alzheimer’s disease and Progressive Supranuclear Palsy are a diverse group of progressive neurodegenerative disorders pathologically defined by inclusions containing aberrantly aggregated, post-translationally modified tau. The tau pathology burden correlates with neurodegenera...

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Vydáno v:PLoS One
Hlavní autoři: Croft, Cara L., Moore, Brenda D., Ran, Yong, Chakrabarty, Paramita, Levites, Yona, Golde, Todd E., Giasson, Benoit I.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880389/
https://ncbi.nlm.nih.gov/pubmed/29608591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0195211
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