Transthyretin sequesters amyloid beta protein and prevents amyloid formation.

The cardinal pathological features of Alzheimer disease are depositions of aggregated amyloid beta protein (A beta) in the brain and cerebrovasculature. However, the A beta is found in a soluble form in cerebrospinal fluid in healthy individuals and patients with Alzheimer disease. We postulate that...

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Bibliografische gegevens

Gepubliceerd in:	Proc Natl Acad Sci U S A
Hoofdauteurs:	Schwarzman, A L, Gregori, L, Vitek, M P, Lyubski, S, Strittmatter, W J, Enghilde, J J, Bhasin, R, Silverman, J, Weisgraber, K H, Coyle, P K
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	National Academy of Sciences 1994
Onderwerpen:	Research Article
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44607/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8078889/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.18.8368
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