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Transthyretin sequesters amyloid beta protein and prevents amyloid formation.

The cardinal pathological features of Alzheimer disease are depositions of aggregated amyloid beta protein (A beta) in the brain and cerebrovasculature. However, the A beta is found in a soluble form in cerebrospinal fluid in healthy individuals and patients with Alzheimer disease. We postulate that...

詳細記述

保存先:
書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Schwarzman, A L, Gregori, L, Vitek, M P, Lyubski, S, Strittmatter, W J, Enghilde, J J, Bhasin, R, Silverman, J, Weisgraber, K H, Coyle, P K
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 1994
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44607/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8078889/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.18.8368
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