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Transthyretin sequesters amyloid beta protein and prevents amyloid formation.

The cardinal pathological features of Alzheimer disease are depositions of aggregated amyloid beta protein (A beta) in the brain and cerebrovasculature. However, the A beta is found in a soluble form in cerebrospinal fluid in healthy individuals and patients with Alzheimer disease. We postulate that...

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Gorde:
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Schwarzman, A L, Gregori, L, Vitek, M P, Lyubski, S, Strittmatter, W J, Enghilde, J J, Bhasin, R, Silverman, J, Weisgraber, K H, Coyle, P K
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 1994
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44607/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8078889/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.18.8368
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