Transthyretin sequesters amyloid beta protein and prevents amyloid formation.

The cardinal pathological features of Alzheimer disease are depositions of aggregated amyloid beta protein (A beta) in the brain and cerebrovasculature. However, the A beta is found in a soluble form in cerebrospinal fluid in healthy individuals and patients with Alzheimer disease. We postulate that...

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Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Schwarzman, A L, Gregori, L, Vitek, M P, Lyubski, S, Strittmatter, W J, Enghilde, J J, Bhasin, R, Silverman, J, Weisgraber, K H, Coyle, P K
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1994
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44607/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8078889/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.18.8368
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