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Identification of an epithelial cell receptor responsible for Clostridium difficile TcdB-induced cytotoxicity
Clostridium difficile is the leading cause of hospital-acquired diarrhea in the United States. The two main virulence factors of C. difficile are the large toxins, TcdA and TcdB, which enter colonic epithelial cells and cause fluid secretion, inflammation, and cell death. Using a gene-trap insertion...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4460460/ https://ncbi.nlm.nih.gov/pubmed/26038560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1500791112 |
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