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Clostridium difficile Toxins TcdA and TcdB Cause Colonic Tissue Damage by Distinct Mechanisms

As the major cause of antibiotic-associated diarrhea, Clostridium difficile is a serious problem in health care facilities worldwide. C. difficile produces two large toxins, TcdA and TcdB, which are the primary virulence factors in disease. The respective functions of these toxins have been difficul...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Infect Immun
Κύριοι συγγραφείς: Chumbler, Nicole M., Farrow, Melissa A., Lapierre, Lynne A., Franklin, Jeffrey L., Lacy, D. Borden
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology 2016
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5038081/
https://ncbi.nlm.nih.gov/pubmed/27456833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00583-16
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