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Clostridium difficile Toxins TcdA and TcdB Cause Colonic Tissue Damage by Distinct Mechanisms

As the major cause of antibiotic-associated diarrhea, Clostridium difficile is a serious problem in health care facilities worldwide. C. difficile produces two large toxins, TcdA and TcdB, which are the primary virulence factors in disease. The respective functions of these toxins have been difficul...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Chumbler, Nicole M., Farrow, Melissa A., Lapierre, Lynne A., Franklin, Jeffrey L., Lacy, D. Borden
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5038081/
https://ncbi.nlm.nih.gov/pubmed/27456833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00583-16
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