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Clostridium difficile Toxins TcdA and TcdB Cause Colonic Tissue Damage by Distinct Mechanisms

As the major cause of antibiotic-associated diarrhea, Clostridium difficile is a serious problem in health care facilities worldwide. C. difficile produces two large toxins, TcdA and TcdB, which are the primary virulence factors in disease. The respective functions of these toxins have been difficul...

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書目詳細資料
發表在:Infect Immun
Main Authors: Chumbler, Nicole M., Farrow, Melissa A., Lapierre, Lynne A., Franklin, Jeffrey L., Lacy, D. Borden
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5038081/
https://ncbi.nlm.nih.gov/pubmed/27456833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00583-16
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