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α-Synuclein binds the K(ATP) channel at insulin-secretory granules and inhibits insulin secretion

α-Synuclein has been studied in numerous cell types often associated with secretory processes. In pancreatic β-cells, α-synuclein might therefore play a similar role by interacting with organelles involved in insulin secretion. We tested for α-synuclein localizing to insulin-secretory granules and c...

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Detalhes bibliográficos
Publicado no:Am J Physiol Endocrinol Metab
Main Authors: Geng, Xuehui, Lou, Haiyan, Wang, Jian, Li, Lehong, Swanson, Alexandra L., Sun, Ming, Beers-Stolz, Donna, Watkins, Simon, Perez, Ruth G., Drain, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459921/
https://ncbi.nlm.nih.gov/pubmed/20858756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00262.2010
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